Hsp27 regulates podocyte cytoskeletal changes in an in vitro model of podocyte process retraction
Open Access
- 14 January 2002
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 16 (3) , 315-326
- https://doi.org/10.1096/fj.01-0681com
Abstract
Nephrotic syndrome (NS) is characterized by structural changes in the actin-rich foot processes of glomerular podocytes. We previously identified high concentrations of the small heat shock protein h...Keywords
This publication has 35 references indexed in Scilit:
- Heat Shock Proteins: Endogenous Modulators of Apoptotic Cell DeathBiochemical and Biophysical Research Communications, 2001
- Regulation of mouse podocyte process dynamics by protein tyrosine phosphatasesKidney International, 2000
- Major role for active extension in the formation of processes byras-transformed fibroblastsCell Motility, 1999
- In vivo evaluation of hsp27 as an inhibitor of actin polymerization: Hsp27 limits actin stress fiber and focal adhesion formation after heat shockJournal of Cellular Physiology, 1998
- Expression of the 25-kDa heat-shock protein (HSP27) correlates withresistance to the toxicity of cadmium chloride, mercuric chloride, cis-platinum(II)-diammine dichloride, or sodium arsenite in mouse embryonic stem cells transfected with sense or antisense HSP27 cDNAToxicology and Applied Pharmacology, 1996
- Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteinsFEBS Letters, 1992
- Contractile proteins in podocytes: immunocytochemical localization of actin and alpha-actinin in normal and nephrotic rat kidneysVirchows Archiv B Cell Pathology Including Molecular Pathology, 1991
- Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells.The Journal of cell biology, 1989
- Characterization of an inhibitor of actin polymerization in vinculin‐rich fraction of turkey gizzard smooth muscleEuropean Journal of Biochemistry, 1988
- Filamentous actin bundles in the kidneyThe Anatomical Record, 1984