ADDISON'S DISEASE IN A BOY WITH HYPOPARATHYROIDISM*

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Abstract
INTRODUCTION TWO and possibly 3 cases of hypoparathyroidism with Addison's disease have been presented in the literature. Leonard (1) described a patient who had hypoparathyroidism at the age of 3 years. Superimposed adrenal insufficiency occurred at the age of 101/2 years. Postmortem examination verified the clinical impression of hypoparathyroidism and Addison's disease. The second patient, an 8-year-old girl with moniliasis, adrenal insufficiency and superimposed hypoparathyroidism, was mentioned briefly in a preliminary report by Talbot et at. (2). In addition, Sutphin, Albright and McCune (3) presented what seems to be a third patient with these two diseases. Their patient had Addison's disease and tetany with low serum concentrations of calcium and phosphorus. Because of a history of pleural infusion and a positive tuberculin reaction, they suggested that this was probably the result of tuberculous infection. The patient reported here was a 10-year-old boy in whom Addison's disease developed after he had had signs of hypoparathyroidism for five years. It is hoped that this report will shed some light on the etiology of this syndrome and provide information concerning the effect of adrenal insufficiency upon the altered metabolism of hypoparathyroidism treated with vitamin D.