Blood Volume Studies in Normal and Anemic Swine

Publisher Website
Google Scholar
Abstract
Seventy-six red cell, plasma, and total blood volume determinations were made by the P32 method on 31 normal swine. Thirty-three determinations were made on 30 pigs with experimentally induced anemia. Simultaneous plasma volume determinations were made by the Fe59 method on 24 normal swine and 16 animals with anemia. The increase in red cell, plasma, and total blood volume with growth was of lesser magnitude than the gain in body weight. With successive growth the red cell volume per unit of body weight decreased less than the plasma volume or total blood volume. The reduction in red cell volume that occurred in the anemic swine was not compensated by a comparable increase in plasma volume. This resulted in a slightly lower total blood volume in the anemic swine than in the control animals of the same weight. Plasma volumes, when determined by the Fe59 method were somewhat higher than those estimated by the p32 method. This difference was more narked in swine with experimentally induced anemias associated with rapid clearance of Fe59 from the plasma than in the control swine.

This publication has 4 references indexed in Scilit: