A Variant of Parainfluenza Type 2 Virus

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Abstract
Summary Three isolates of hemadsorption virus were recovered from children with respiratory infections in January 1966. The three isolates could not be distinguished from the prototype Greer strain of parainfluenza type 2 virus by the complement-fixation test using antisera against both the new isolate and Greer strain. However, the neutralization test and the hemagglutination-inhibition test revealed a difference between the new isolates and the prototype Greer strain. The antiserum against Greer strain was not inhibitory for the new isolates in the hemagglutination-inhibition test of the latter viruses before and after sonication and also in the neutralization test, whereas ether disruption of the hemagglutinin disclosed a common antigen in the new isolates and the Greer strain. In contrast to this, 6 isolates of 1965 were the same as the Greer strain in all serological tests.