Improvement in Sensitivity of Allele-specific PCR Facilitates Reliable Noninvasive Prenatal Detection of Cystic Fibrosis
- 1 April 2004
- journal article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 50 (4) , 694-701
- https://doi.org/10.1373/clinchem.2003.025981
Abstract
Background: Cell-free fetal DNA circulating in maternal blood has potential as a safer alternative to invasive methods of prenatal testing for paternally inherited genetic alterations, such as cystic fibrosis (CF) mutations.Keywords
This publication has 31 references indexed in Scilit:
- A classification of pregnancy losses after invasive prenatal diagnostic procedures: an approach to allow comparison of units with a different case mixPrenatal Diagnosis, 2003
- Huntington disease–unaffected fetus diagnosed from maternal plasma using QF‐PCRPrenatal Diagnosis, 2003
- Intact fetal cells in maternal plasma: are they really there?The Lancet, 2003
- FetalRHDgenotyping in maternal serum during the first trimester of pregnancyBritish Journal of Haematology, 2002
- Prenatal detection of a cystic fibrosis mutation in fetal DNA from maternal plasmaPrenatal Diagnosis, 2002
- Prenatal exclusion of β thalassaemia major by examination of maternal plasmaThe Lancet, 2002
- First‐trimester fetal sex determination in maternal serum using real‐time PCRPrenatal Diagnosis, 2001
- Prenatal DNA diagnosis of a single-gene disorder from maternal plasmaThe Lancet, 2000
- Fetal DNA in maternal plasma: the prenatal detection of a paternally inherited fetal aneuploidyPrenatal Diagnosis, 2000
- Presence of fetal DNA in maternal plasma and serumThe Lancet, 1997