Heparin enhances the rate of binding of fibronectin to collagen
- 1 May 1980
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 187 (2) , 521-524
- https://doi.org/10.1042/bj1870521
Abstract
125I-labelled fibronectin is shown to bind to both native and denatured collagen immobilized on Sephadex beads in reactions that exhibit different kinetics. The rates of both reactions were enhanced by the presence of heparin or highly sulphated dextran sulphate but not by other glycosaminoglycans or dextran sulphates having low sulphate contents.This publication has 17 references indexed in Scilit:
- Fibronectins—adhesive glycoproteins of cell surface and bloodNature, 1978
- Affinity of fibronectin to collagens of different genetic types and to fibrinogen.The Journal of Experimental Medicine, 1978
- Identification of the sites in collagen α-chains that bind serum anti-gelatin factor (cold-insoluble globulin)Biochemical Journal, 1978
- Cold-Insoluble Globulin (Fibronectin), IV Affinity to Soluble Collagen of Various TypesBiological Chemistry, 1978
- Plasma membrane glycoprotein which mediates adhesion of fibroblasts to collagenNature, 1976
- Anticoagulant activity of heparin: Separation of high‐activity and low‐activity heparin species by affinity chromatography on immobilized antithrombinFEBS Letters, 1976
- Recongnition by guinea-pig peritoneal exudate cells of conformationally different states of the collagen molecule.1976
- The binding of chondroitin sulphate to collagenFEBS Letters, 1975
- Isolation of a collagen-dependent cell attachment factorNature, 1974
- Non‐Aggregated Tropocollagen at Physiological pH and Ionic StrengthEuropean Journal of Biochemistry, 1972