Minimal Dosage of Iodide Required To Suppress Uptake of Iodine-131 by Normal Thyroid

19 October 1962

journal article
research article
Published by American Association for the Advancement of Science (AAAS) in Science

Vol. 138 (3538) , 430-431
https://doi.org/10.1126/science.138.3538.430

Abstract

Sodium iodide was given in increasing doses to mentally defective children with normal thyroid function. Maximal suppression of iodine-131 uptake was achieved with 1500 to 2000 micrograms of iodide per square meter of body surface per day, but quickly rebounded when iodide was discontinued. This minimal effective dose is important if countermeasures against fallout are employed.

Keywords

IODIDES
IODINE ISOTOPES
THYROID GLAND

This publication has 3 references indexed in Scilit:

Iodine-131 Dose from Soviet Nuclear Tests
Science, 1962
GOITER FROM PROLONGED INGESTION OF IODIDE*
Journal of Clinical Endocrinology & Metabolism, 1956
TWO CASES OF MYXŒDEMA ATTRIBUTED TO IODIDE ADMINISTRATION
The Lancet, 1953