Stereocontrolled Conversion of 3-Unsubstituted Isoxazole Compounds into Z-β-Siloxyacrylonitriles. A New Method for the Regioselective Synthesis of β-Enaminoketones
- 1 April 1995
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 25 (7) , 1005-1014
- https://doi.org/10.1080/00397919508012661
Abstract
The stereoselective synthesis of Z-β-siloxyacrylonitriles via base-induced ring cleavage of isoxazole precursors is described. Z-β-siloxyacrylonitriles react with organolithium compounds to give high yields of β-enaminoketones 1.Keywords
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