LIPOIDS AND IMMUNOLOGICAL REACTIONS
Open Access
- 1 October 1935
- journal article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 62 (4) , 485-503
- https://doi.org/10.1084/jem.62.4.485
Abstract
It has been demonstrated that the removal of lipoids from Type I antipneumococcus horse serum causes a loss of the visible phenomena of type specific agglutination and precipitation, and in the case of rabbit serum a marked reduction in these properties. Initial activity of the type specific antibody can be restored to extracted immune horse serum by the addition of lecithin, and to rabbit serum by the addition of cephalin. The significance of these observations in respect to the relation of phospholipins to the type specific reactions of antipneumococcus serum is discussed.Keywords
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