The Metabolism of 3,3′-Diiodothyronine in Man*
- 1 January 1980
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 50 (1) , 148-151
- https://doi.org/10.1210/jcem-50-1-148
Abstract
The production rate of 3,3′-Diiodothyronine (3,3′-T2) was measured in five healthy subjects after a single injection of [125I]3,3′-T2. The [I25I]3,3′-T2 was measured by immunoprecipitation. To reduce the large amount of nonspecific serum radioactivity (iodides, 3,3′-T2 metabolites, and proteinbound iodine), the sera were treated before the immunoprecipitation with an anion exchanger and polyethylene glycol (final concentration, 10%). The noncompartmental analysis of the data gave the following results: MCR, 0.52 ± 0.07 liters⁄min or 926 ± 142 liters⁄day (mean ± SD); and production rate, 23.7 ± 8.2 ng⁄min or 34 ± 12 µg⁄day.Keywords
This publication has 1 reference indexed in Scilit:
- Thyroidal and Peripheral Production of Thyroid HormonesAnnals of Internal Medicine, 1977