Events per person year

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# A decrease in multiple events may be missed {#article-title-2} EDITOR,—Jurgen Windeler and Stefan Lange describe the “new measure” invented in 1982 to describe osteoporotic fractures in the context of clinical trials—namely, the frequency of vertebral fracture.1 They suggest that the number of patients developing vertebral fractures is a more appropriate end point. In their review they neglect to mention that the problems with this approach are well recognised,2 3 though perhaps not universally applied. Nor is the fallacy ignored by some registration authorities, and in some countries the test agents to which …