Clinical Experiences with Oral Ethinyl Estradiol

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Abstract
Results of treatment of 18 menopausal patients over a period of 21 mos. are presented. All patients were under treatment 2 mos. or more and 1 for 13 mos. Only 1 patient exhibited what might be considered a toxic reaction to ethinyl estradiol, in that urticarial lesions occurred after taking a small amt. of the drug. The patient had had the same reaction to diethylstilbestrol. Toxic reactions must be evaluated before concluding that such reactions are not a functional manifestation of a neurotic type. Finally, relatively small doses of ethinyl estradiol are effective in alleviating symptoms of the menopause and with its use uniformly good results were obtained.