APB Selectively Reduces Visual Responses in Goldfish to High Spatiotemporal Frequencies
- 1 January 1989
- journal article
- Published by Maximum Academic Press in Visual Neuroscience
- Vol. 2 (1) , 15-18
- https://doi.org/10.1017/s0952523800004272
Abstract
Visual responses of goldfish to rotating square-wave gratings were recorded before and after intraocular injection of 2-amino-4-phosphonobutyric acid (APB). High doses of APB reduced the rate of optokinetic nystagmus (OKN) to a relatively high spatial frequency grating moving at a high temporal frequency. Responses to a low spatial frequency grating were not altered, nor were responses to the higher spatial frequency when it rotated slowly. The effects of APB were transient and lasted no longer than 3 d. We conclude that APB reduces OKN to high spatiotemporal frequencies in goldfish.Keywords
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