Oral 1-O-octadecyl-2-O-benzyl-sn-glycero-3-cidofovir targets the lung and is effective against a lethal respiratory challenge with ectromelia virus in mice

This publication has 10 references indexed in Scilit:

• Activities of Alkoxyalkyl Esters of Cidofovir (CDV), Cyclic CDV, and ( S )-9-(3-Hydroxy-2-Phosphonylmethoxypropyl)Adenine against Orthopoxviruses in Cell Monolayers and in Organotypic Cultures
  Antimicrobial Agents and Chemotherapy, 2006
• Comparative Activities of Lipid Esters of Cidofovir and Cyclic Cidofovir against Replication of Herpesviruses In Vitro
  Antimicrobial Agents and Chemotherapy, 2005
• Comparison of the Antiviral Activities of Alkoxyalkyl and Alkyl Esters of Cidofovir against Human and Murine Cytomegalovirus Replication In Vitro
  Antimicrobial Agents and Chemotherapy, 2005
• Oral Treatment of Cowpox and Vaccinia Virus Infections in Mice with Ether Lipid Esters of Cidofovir
  Antimicrobial Agents and Chemotherapy, 2004
• Efficacy of oral active ether lipid analogs of cidofovir in a lethal mousepox model
  Virology, 2004
• Esterification of cidofovir with alkoxyalkanols increases oral bioavailability and diminishes drug accumulation in kidney
  Antiviral Research, 2003
• Increased Antiviral Activity of 1-O-Hexadecyloxypropyl-[2-14C]cidofovir in MRC-5 Human Lung Fibroblasts Is Explained by Unique Cellular Uptake and Metabolism
  Molecular Pharmacology, 2003
• Alkoxyalkyl Esters of Cidofovir and Cyclic Cidofovir Exhibit Multiple-Log Enhancement of Antiviral Activity against Cytomegalovirus and Herpesvirus Replication In Vitro
  Antimicrobial Agents and Chemotherapy, 2002
• Enhanced Inhibition of Orthopoxvirus Replication In Vitro by Alkoxyalkyl Esters of Cidofovir and Cyclic Cidofovir
  Antimicrobial Agents and Chemotherapy, 2002
• MEASUREMENT OF THE RESPIRATORY VOLUMES OF LABORATORY ANIMALS
  American Journal of Physiology-Legacy Content, 1947