In vitro and in vivo removal of anti-A erythrocyte antibody by adsorption to a synthetic immunoadsorbent

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Abstract
A solid-phase immunoadsorbent column using blood group A trisaccharide was tested in vitro and in vivo in dogs. This column specifically removed anti-A antibody from human plasma in vitro and in vivo in dogs specifically immunized with synthetic human blood group A trisaccharide. Apparently this technique will be useful in removing anti-A and B antibody in marrow transplant recipients of incompatible marrow.