Barbiturate Protection in Cerebral Hypoxia

Publisher Website
Google Scholar
Abstract
Recent animal work has indicated that barbiturate anesthesia protects the brain against several types of hypoxic insults. This paper reviews these data, examines suggested mechanisms, and considers possible clinical implications for humans. The effects of hypoxia on cerebral metabolism, as well as past experience with non-pharmacologic attempts to achieve cerebral protection with hyperventilation ahd hypothermia are discussed.