Mononuclear Cells Contain Human Transfer Factor as Assayed Locally on the Skin of Dogs
Open Access
- 1 August 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 123 (2) , 590-593
- https://doi.org/10.4049/jimmunol.123.2.590
Abstract
We prepared transfer factor from mononuclear (M) cells and polymorphonuclear (PMN) cells by sieving cell lysates through a P-2 Biogel column. By assaying column fractions by their ability to induce a local delayed-type reaction to antigen in canine skin, we determined that mononuclear cells most consistently contained skin activity. The elution patterns from P-2 Biogel of PMN or M-enriched preparations were less complex and much different from that seen with whole leukocytes.This publication has 8 references indexed in Scilit:
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