Detection and immunochemical characterization of a primate type C retrovirus-related p30 protein in normal human placentas.

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Abstract
Of 14 specimens of normal human term placentas analyzed by 1- or 2-dimensional electrophoresis and immunoblotting, 12 contain a protein or polypeptide of .apprx. 30,000 daltons that is antigenically cross-reactive with p30 core protein of the simian sarcoma-associated virus/gibbon ape leukemia virus primate retrovirus group and is physicochemically similar to reference murine and primate type C retrovirus p30. This finding may lead to an understanding of endogenous type C retrovirus gene expression in humans.