The Intestinal Excretion of Digitoxin in the Rat

Abstract
Rats given a parenteral injection of digitoxin (1 µg. per gram of body weight) were found to excrete approximately 15 to 18 per cent of the dose in their feces. This fecal digitoxin however came from the bile, and there was no evidence of any active secretion of the glycoside by the bowel wall itself.