Synthesis of a cephalosporin analogue
- 1 January 1977
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 12,p. 1421-1425
- https://doi.org/10.1039/p19770001421
Abstract
The recently developed photolytic Wolff rearrangement of 3-diazopyrrolidine-2,4-diones for the synthesis of β-lactams has been used to prepare cis(6H,7H)-8-oxo-7-phenylacetamido-1-aza-4-thiabicyclo[4.2.0]oct-2-ene-2-carbaldehyde (3; R = CHO), which showed antibacterial activity against Staphylococcus aureus.This publication has 3 references indexed in Scilit:
- Synthesis of cephalosporin-4-aldehydesJournal of Medicinal Chemistry, 1977
- Deacetylcephalosporin CBiochemical Journal, 1961
- CITRUS ACETYLESTERASE1947