Inhibition of Mumps and Influenza B Virus Multiplication by Synthetic Poly-D-Lysine.

Abstract
Poly-D-lysine, though ten times more toxic, inhibited mumps and influenza B Lee strain viruses to approximately the same extent as poly-L-lysine in the allantoic sac of the chick embryo. As little as 0.001 mg per embryo of either lysine polypeptide was sufficient to inhibit high levels of viral infection. Evidence was obtained which suggested the existence in allantoic fluid of enzymes which hydrolyze both poly-D-lysine and poly-L-lysine.

This publication has 3 references indexed in Scilit: