Analysis of Intrafamilial Correlations, Serum Levels of IGM and the Human X-Chromosome

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Abstract
The serum concentrations of immunoglobulin M (IgM) were measured in a sample of 93 monozygotic twin pairs, their spouses, and their offsprings. The hypothesis that the human X chromosome carries genes that control the levels of IgM was tested with two different approaches neither one of which provided conclusive evidence to support the IgM X-linked gene hypothesis.