Metathesis Reactions in Total Synthesis
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- 8 July 2005
- journal article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 44 (29) , 4490-4527
- https://doi.org/10.1002/anie.200500369
Abstract
With the exception of palladium-catalyzed cross-couplings, no other group of reactions has had such a profound impact on the formation of carbon-carbon bonds and the art of total synthesis in the last quarter of a century than the metathesis reactions of olefins, enynes, and alkynes. Herein, we highlight a number of selected examples of total syntheses in which such processes played a crucial role and which imparted to these endeavors certain elements of novelty, elegance, and efficiency. Judging from their short but impressive history, the influence of these reactions in chemical synthesis is destined to increase.Keywords
This publication has 402 references indexed in Scilit:
- Biomimetic Total Synthesis of Litseaverticillols A, C, D, F, and G: Singlet-Oxygen-Initiated CascadesAngewandte Chemie, 2003
- A Self-Generating, Highly Active, and Recyclable Olefin-Metathesis CatalystAngewandte Chemie International Edition in English, 2002
- Ein selbstgenerierender, hochaktiver und wiederverwendbarer Katalysator für die OlefinmetatheseAngewandte Chemie, 2002
- Catalytic Asymmetric Olefin MetathesisChemistry – A European Journal, 2001
- Olefinmetathese und mehrAngewandte Chemie, 2000
- Hochaktive Rutheniumkatalysatoren für die Olefinmetathese: die Synergie N-heterocyclischer Carbene und koordinativ labiler LigandenAngewandte Chemie, 1999
- Total Synthesis of (−)-MucocinAngewandte Chemie International Edition in English, 1999
- Alkyne Metathesis as a New Synthetic Tool: Ring-Closing, Ring-Opening, and AcyclicAngewandte Chemie International Edition in English, 1999
- Die Totalsynthese von Epothilon A: der Zugang durch OlefinmetatheseAngewandte Chemie, 1997
- Totalsynthese von (—)‐Epothilon AAngewandte Chemie, 1996