Oxidative activation of the thiophene ring by hepatic enzymes
- 1 March 1990
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 39 (5) , 911-918
- https://doi.org/10.1016/0006-2952(90)90207-2
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- The in Vitro and in Vivo Metabolism of Morantel in Cattle and Toxicology SpeciesDrug Metabolism Reviews, 1987
- Absorption, excretion and metabolism of tiquizium bromide in dogs, and relationship between pharmacological effect and plasma levels of unchanged drugXenobiotica, 1985
- Metabolic hydroxylation of the thiophene ring: Isolation of 5-hydroxy-tienilic acid as the major urinary metabolite of tienilic acid in man and ratBiochemical Pharmacology, 1984
- Metabolism of tenoxicam in ratsXenobiotica, 1984
- Biochemical Mechanisms in Chemical-Induced Lung Injury: Roles of Metabolic ActivationCRC Critical Reviews in Toxicology, 1980
- Renal and hepatic necrosis after metabolic activation of 2-substituted furans and thiophenes, including furosemide and cephaloridineToxicology and Applied Pharmacology, 1977
- Synthese d'un diuretique marque au carbone 14: Acide dichloro‐2,3 [thenoyl‐2 (14C = 0)]‐4 phenoxy acetique (D.C.I. acide tiénilique)Journal of Labelled Compounds and Radiopharmaceuticals, 1976
- Pharmacokinetic study of 2,3-dichloro 4-[2-thienyl keto14C] phenoxyacetic acid (Tienilic acid) in animals I. Localisation, distribution and elimination of14C Tienilic acid in animalsEuropean Journal of Drug Metabolism and Pharmacokinetics, 1976
- Arene Oxides: A New Aspect of Drug MetabolismScience, 1974
- The Metabolism of Thiophen in the Rabbit and the RatXenobiotica, 1971