Literature mining in support of drug discovery
Open Access
- 11 July 2008
- journal article
- review article
- Published by Oxford University Press (OUP) in Briefings in Bioinformatics
- Vol. 9 (6) , 479-492
- https://doi.org/10.1093/bib/bbn035
Abstract
The drug discovery enterprise provides strong drivers for data integration. While attention in this arena has tended to focus on integration of primary data from omics and other large platform technologies contributing to drug discovery and development, the scientific literature remains a major source of information valuable to pharmaceutical enterprises, and therefore tools for mining such data and integrating it with other sources are of vital interest and economic impact. This review provides a brief overview of approaches to literature mining as they relate to drug discovery, and offers an illustrative case study of a ‘lightweight’ approach we have implemented within an industrial context.Keywords
This publication has 80 references indexed in Scilit:
- Extracting interactions between proteins from the literatureJournal of Biomedical Informatics, 2008
- MScanner: a classifier for retrieving Medline citationsBMC Bioinformatics, 2008
- Database resources of the National Center for Biotechnology InformationNucleic Acids Research, 2007
- The BioGRID Interaction Database: 2008 updateNucleic Acids Research, 2007
- Automating document classification for the Immune Epitope DatabaseBMC Bioinformatics, 2007
- Frontiers of biomedical text mining: current progressBriefings in Bioinformatics, 2007
- Global reconstruction of the human metabolic network based on genomic and bibliomic dataProceedings of the National Academy of Sciences, 2007
- MINT: the Molecular INTeraction databaseNucleic Acids Research, 2006
- Literature mining for the biologist: from information retrieval to biological discoveryNature Reviews Genetics, 2006
- An upper‐level ontology for the biomedical domainComparative and Functional Genomics, 2003