Relationship in Mice of Intestinal Emptying Time and Natural Resistance to Pig Ascaris Infection
- 20 January 1950
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 111 (2873) , 62-63
- https://doi.org/10.1126/science.111.2873.62
Abstract
The M.I .D. for mice of mature embryonated eggs was found to be about 30,000, indicating a strong natural resistance to infection with Ascaris lumbricoides suum. When mice were treated with morphine sulfate (1%) to artificially slow intestinal emptying time, they were rendered more susceptible to infection with ascaris eggs than untreated controls given the same number of eggs. The reduced intestinal emptying time presumably allows greater numbers of eggs to hatch than in control animals.Keywords
This publication has 5 references indexed in Scilit:
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- The Probable Explanation for the Difference in the Localization of Adult Trichinella spiralis in Young and Old MiceJournal of Parasitology, 1949
- The Relationship in Mice of Intestinal Emptying Time and Natural Resistance to HymenolepisJournal of Parasitology, 1947