195Pt NMR Determination of the Enantiomeric Purity and Absolute Configuration of Trisubstituted Allenes by Using [PtCl3(C2H4)]-[(S,S)-(1-NpMeCH)2NH2]+ as CDA
- 21 December 2000
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 3 (2) , 205-207
- https://doi.org/10.1021/ol000335l
Abstract
The ionic CDA [PtCl3(C2H4)]-[(S,S)-(1-NpMeCH)2NH2]+ produces, on exchange of its coordinated ethylene by chiral trisubstituted allenes, diastereoisomeric mixtures originating distinct 195Pt NMR resonances for the complexed enantiomers, thus allowing the determination of the enantiomeric purity. A reproducible correlation between relative positions of platinum signals due to the complexed enantiomers and their absolute configuration has been found.Keywords
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