Effect of Aerosol Age on the Infectivity of AirbornePasteurella tularensisforMacaca mulattaand Man

Abstract
Sawyer, WilliamD. (U.S. Army Medical Unit, Fort Detrick, Frederick, Md.),Joseph V. Jemski, Arthur L. Hogge, Jr., Henry T. Eigelsbach, Elwood K. Wolfe, Harry G. Dangerfield, William S. Gochenour, Jr., and Dan Crozier. Effect of aerosol age on the infectivity of airbornePasteurella tularensisforMacaca mulattaand man. J. Bacteriol.91:2180–2184. 1966.—In aging aerosols ofPasteurella tularensisSCHU-S4, the respiratory infectivity for man andMacaca mulattadecreased more rapidly than the viability of the organisms. Infectivity was diminished after 120 min, and was reduced 10-fold after 180 min. These findings confirmed previous observations made in mice and guinea pigs, and also revealed that smaller losses of infectivity were detectable in the primate hosts.