Two New Quassinoids from Simaba multiflora Fruits

Abstract
Two new quassinoids, 13,18-dehydro-6.alpha.-senecioyloxychaparrin (4) and 12-dehydro-6.alpha.-senecioyloxychaparrin (5), have been isolated from Simaba multiflora fruits. Their structures were deduced from spectral data. 1H-13C-2-D chemical-shift correlation nmr was applied to the structural elucidation of the antileukemic quassinoid 4.