Accuracy of a Radiopotassium Dilution (Stewart Principle) Method for the Measurement of Cardiac Output

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Abstract
The accuracy of a radiopotassium method for measurement of cardiac output was determined in dogs by comparison of results with those obtained by the Fick procedure using O2. The K42 method appears to have no systematic error and a random error of [plus or minus] 5% in normal animals, no systematic error and a [plus or minus] 5% random error under varied exptl. conditions. The simplicity of the technique and the advantages accruing from the recirculation of radioactivity are pointed out.