Detection of IgA class antibody to hepatitis E virus in serum samples from patients with hepatitis E virus infection
- 1 August 1993
- journal article
- research article
- Published by Wiley in Journal of Medical Virology
- Vol. 40 (4) , 334-338
- https://doi.org/10.1002/jmv.1890400414
Abstract
A newly developed assay for IgA class antibody to hepatitis E virus (IgA anti-HEV) was used to study 145 serum samples collected during an outbreak of an enterically transmitted hepatitis that occurred in 3 villages in the lower Shebeli region of Southern Somalia between January, 1988 and November, 1989. A total of 52.4% of the afflicted patients were found positive for IgA anti-HEV, and 73.1% of these were also positive for IgM. Both antibodies disappeared during the convalescence period. Similar results were also seen in serum obtained from sporadic cases of acute waterborne hepatitis in Pakistan.Keywords
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