Temperature-Sensitive Mutations in Drosophila melanogaster , VIII. The Homeotic Mutant, ss a40a
- 1 June 1971
- journal article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 68 (6) , 1307-1311
- https://doi.org/10.1073/pnas.68.6.1307
Abstract
There exists in Drosophila a class of mutations called "homeotic" that cause changes in determination of the imaginal discs. The homeotic mutant, ss(a40a), was found to have a temperature-sensitive transformation of the arista segment of the antennal complex to a tarsus of the leg. In a selected stock penetrance was complete, so that at 29 degrees C normal aristae were produced, whereas at 17 degrees C complete tarsi developed in all flies. "Temperature-shift" studies revealed a temperature-sensitive period in the third larval instar. The temperature-initiated action of ss(a40a) does not appear to result from a simple wave or gradient of determination passing through the disc. Shifts up during the temperature-sensitive period yielded leg tissue proximally, which increased distally with progressively later shifts. Shifts down yielded leg tissue at the aristal base, which retreated with later shifts.Keywords
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