Effects of Short-term High-carbohydrate Feeding on Serum Triglyceride of Children with Familial Hypercholesterolaemia

Abstract
In 5 children with familial hypercholesterolaemia, serum triglyceride levels, which were initially normal, rose after three days on a high-carbohydrate diet; a similar response occurred in one child with normal serum lipoproteins. These observations suggest that a rise in serum triglyceride on high-carbohydrate feeding is a normal finding in children and therefore should not be used as a test for the diagnosis of the pathological state of `carbohydrate-induced hypertriglyceridaemia'. The findings in familial hypercholesterolaemia indicate that diets used in the treatment of this condition should not contain an unduly high proportion of carbohydrate.