Selective Attachment of Oligonucleotides to Interleukin-1β and Targeted Delivery to Cells
- 1 October 1990
- journal article
- research article
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 9 (7) , 957-966
- https://doi.org/10.1080/07328319008045211
Abstract
Conjugates between oligodeoxyribonucleotides and an interleukin-1β mutant protein have been constructed using a heterobifunctional cross-linker. These protein-DNA conjugates had conserved binding activity to the interleukin-1 receptor. The oligonucleotide hybridization properties were unchanged.This publication has 18 references indexed in Scilit:
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