A Short Synthesis of Gastrolactone
- 1 August 1994
- journal article
- research article
- Published by Taylor & Francis in Natural Product Letters
- Vol. 5 (1) , 61-68
- https://doi.org/10.1080/10575639408043936
Abstract
Gastrolactone, a component from the larval defensive secretion of the chrysomelid beetle Gastrophysa cyanea, was synthesized in four steps from citral. The key step was an enal-enamine [2+4] cycloaddition. Gastrolactol, the lactol form of plagiodial, was an intermediate in the synthetic sequence.Keywords
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