DIAGNOSTIC LIMITS FOR THYROIDAL RADIOIODINE UPTAKE RATES*

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Abstract
The thyroidal I131 uptake rate was measured in 1,116 Australian subjects whose thyroidal status was established at the same time. The logarithm of the uptake rate factor for various functional groups was found to be normally distributed. Diagnostic borderlines are described for premenopausal and postmenopausal females with and without goiter, and for males with and without goiter. The I131 uptake rate was found to decrease progressively with age in male subjects. In females it remained constant until the age of the menopause, following which a progressive decrease was seen. In 76 per cent of subjects unaffected by prior medication a clear diagnosis was established by a single thyroidal I131 uptake test.