Anatomical and Functional Integrity of Adrenal Cortices Not Dependent on Structural Integrity of Ventral Hypothalamus

Publisher Website
Google Scholar
Abstract
The ventral half of the hypothalamus and proximal 2/3 of the hypophysial stalk including all vascular channels located in the junctional area between the hypophysis and hypothalamus were completely destroyed by thermocoagulation . (ventral hypothalamectomy) in a group of 10 dogs. Verification of the extent of the tissue defect was made, at the termination of an individual experiment, by serial sectioning of the brain and appropriate staining of representative sections. The animals were maintained for months subsequent to hypothalamectomy and during this period the presence or absence of physiological deficits were assessed. The ventral hypothalamectomy did not cause any obvious adrenal cortical atrophy nor was there any detectable inadequacy of adrenal cortical function.