Rapid infusion of intravenous immune globulin in patients with neuromuscular disorders
- 13 November 2001
- journal article
- Published by Wolters Kluwer Health in Neurology
- Vol. 57 (9) , 1699-1701
- https://doi.org/10.1212/wnl.57.9.1699
Abstract
The safety and efficiency of a novel method of rapid-infusion IV immunoglobulin (IVIg) were retrospectively reviewed in 50 patients with neuromuscular disorders. There were 89 adverse events after 341 rapid infusions (26%), 3.5% of which were considered to be major (requiring hospitalization) and 66% minor. All patients recovered without sequelae, and there were no deaths. Fourteen of 17 patients (82%) receiving maintenance therapy preferred rapid IVIg infusion because of its convenience. Rapid-infusion IVIg can be given safely and conveniently in many patients with neuromuscular disorders.Keywords
This publication has 9 references indexed in Scilit:
- Intravenous immunoglobulin in the treatment of autoimmune neuromuscular diseases: Present status and practical therapeutic guidelinesMuscle & Nerve, 1999
- Intravenous immunoglobulin treatment in children with Guillain-Barré syndromeEuropean Journal of Paediatric Neurology, 1997
- Side Effects of High-Dose Intravenous ImmunoglobulinsClinical Neuropharmacology, 1997
- Complications of intravenous immune globulin treatment in neurologic diseaseNeurology, 1996
- Complications of intravenous gammaglobulin in neuromuscular and other diseasesMuscle & Nerve, 1996
- Binding of cytokines to pharmaceutically prepared human immunoglobulin.Journal of Clinical Investigation, 1993
- A Single Intravenous Infusion of Gamma Globulin as Compared with Four Infusions in the Treatment of Acute Kawasaki SyndromeNew England Journal of Medicine, 1991
- Mechanism of therapeutic effect of high-dose intravenous immunoglobulin. Attenuation of acute, complement-dependent immune damage in a guinea pig model.Journal of Clinical Investigation, 1989
- 1040 Prophylactic infusions with an unmodified intravenous immunoglobulin product causing few side-effects in patients with antibody deficiency syndromesInfection, 1985