Treatment of Rheumatoid Arthritis by Intramuscular Triamcinolone Acetonide and Triamcinolone Diacetate

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Abstract
Triamcinolone acetonide (TActn) and triamcinolone diacetate (TDac) were injected intramuscularly in 100-mg doses into 36 patients with rheumatoid arthritis. There were 68 injections of the acetonide derivative and 44 of the diacetate. Satisfactory improvement lasted an average of 20.2 days after an injection of triamcinolone acetonide and 16.2 days after an injection of triamcinolone diacetate. The results from this form of treatment compared very favorably with those from previous oral steroid administration, and in approximately 25% of cases was more satisfactory. Undesirable side-effects were possibly slightly diminished, but a further long-term study would be required for final evaluation.