Primary Aldosteronism with Malignant Hypertension

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Abstract
THE hypertension seen in all reported cases of primary aldosteronism caused by an adrenal adenoma has been of a benign and not rapidly progressive nature.1 On the other hand, an increased secretion of aldosterone regularly occurs with malignant hypertension,2 but is considered a secondary phenomenon associated with bilateral adrenocortical hyperplasia.3 The occurrence of malignant hypertension in a patient found to have a solitary adrenocortical tumor at autopsy was reported by Flynn,4 but the clinical and laboratory features were not diagnostic of primary aldosteronism and no urinary or tumor measurements of aldosterone were performed. Three patients have been found to have . . .

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