The assimilation of amino acids by bacteria. 17. Synthesis of glutathione by extracts of Escherichia coli
- 1 October 1953
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 55 (3) , 441-444
- https://doi.org/10.1042/bj0550441
Abstract
Cell-free extracts of Escherichia coli synthesize glutathione from glutamic acid, cysteine and glycine in the presence of K phosphate, hexose diphosphate, adenosine triphosphate, diphosphopyridine nucleotide and Mg ions. Results of kinetic studies on the reaction are given. Penicillin, bacitracin, Terramycin, aureomycin, chloramphenicol, neomycin, polymyxin, streptomycin, and dihydrostreptomycin, have no effect on the synthesis at concns. of 100 [mu]g./ml.Keywords
This publication has 9 references indexed in Scilit:
- The assimilation of amino-acids by bacteria. 14. Nucleic acid and protein synthesis in Staphylococcus aureusBiochemical Journal, 1953
- The assimilation of amino-acids by bacteria. 15. Actions of antibiotics on nucleic acid and protein synthesis in Staphylococcus aureusBiochemical Journal, 1953
- National Academy of Sciences: Abstracts of Papers Presented at the Annual Meeting April 28-30, 1952, Washington, D. C.Science, 1952
- Relationship of Growth-Phase to the Reducing Activity of Bacterial CellsNature, 1951
- Metabolism of glutathione. IV. Activators and inhibitors of the hydrolysis of glutathione.1951
- ENZYMATIC SYNTHESIS OF GLUTATHIONEJournal of Biological Chemistry, 1951
- A PRESS FOR DISRUPTING BACTERIA AND OTHER MICRO-ORGANISMS1951
- Synthesis of Peptides in Enzymic Reactions involving GlutathioneNature, 1950
- RELATIONSHIP OF THIOL STRUCTURES TO REACTION WITH ANTIBIOTICSJournal of Biological Chemistry, 1946