Evaluation of phosphinic acid derivatives as reagents for amine protection in peptide synthesis
- 1 January 1985
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 6,p. 1217-1226
- https://doi.org/10.1039/p19850001217
Abstract
The results of a kinetic study of the acid-catalysed methanolysis of a series of N-(2-phenyl-ethyl)phosphinamides incorporating selected substituents on phosphorus have been evaluated in order to define the optimum reagent and conditions for amine protection of α-amino acids during peptide synthesis.This publication has 4 references indexed in Scilit:
- Application of diphenylphosphinic carboxylic mixed anhydrides to peptide synthesisJournal of the Chemical Society, Perkin Transactions 1, 1985
- Phosphinamides: a new class of amino protecting groups in peptide synthesisJournal of the Chemical Society, Perkin Transactions 1, 1984
- Peptides—XXXIITetrahedron, 1979
- Phosphorus-31 Nuclear Magnetic Resonance Spectra of Phosphorus Compounds.Journal of Chemical & Engineering Data, 1962