THE RENAL CLEARANCE OF CHORIONIC GONADOTROPIC HORMONE IN PREGNANCY, IN NEOPLASM OF THE TESTIS AND IN HYDATIDIFORM MOLE*

Abstract
The renal clearance of chorionic gonadotrophin was detd. during pregnancy, in hydatidiform mole, and in testicular chorioma. The mean clearance in pregnancy was 0.38 ml. per min., while closely similar values were observed in hydatidiform mole and in testicular chorioma. The constancy of values obtained in the 3 trimesters of pregnancy indicates that the remarkable fluctuation of chorionic gonadotrophin in pregnancy is due to changes in rates of destruction or of formation and not to differences in renal excretion.

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