Women in Clinical Trials — A Portfolio for Success

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Abstract
Just a decade ago, in September 1990, public and political concern about the underrepresentation of women in major clinical trials,1 especially trials focusing on cardiovascular disease, resulted in the establishment of the Office of Research on Women's Health by the National Institutes of Health (NIH). The mission of the office was to set an agenda for research on women's health and to ensure that women and members of minority groups would be included in clinical research funded by the NIH. Three years later, the NIH Revitalization Act required that the NIH strengthen its policies to ensure not only that women . . .