THE CHOLINERGIC COMPONENT IN THE REFLEX VASODILATATION ELICITED BY STIMULATION OF THE DEPRESSOR NERVES IN THE RABBIT
Open Access
- 19 July 1976
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 57 (3) , 375-379
- https://doi.org/10.1111/j.1476-5381.1976.tb07676.x
Abstract
1 The effects of the stimulation of the cephalic endings of the depressor nerve on the resistance in the perfused hindlimb were studied in the rabbit. 2 The vasodilatation thus elicited in the perfused hindlimb was reduced either by administration of guanethidine or by sympathectomy and abolished by subsequent treatment with atropine. 3 These data confirm the existence of two components in the genesis of the reflex vasodilatation: a passive component, due to the inhibition of sympathetic discharge, and an active component which in the rabbit is cholinergic in nature.Keywords
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