Control of Large‐Scale Plasma Thawing for Recovery of Cryoprecipitate Factor VIII1
- 1 April 1982
- journal article
- research article
- Published by Wiley in Vox Sanguinis
- Vol. 42 (4) , 180-189
- https://doi.org/10.1111/j.1423-0410.1982.tb01093.x
Abstract
Cryoprecipitation is commonly used as the primary step in the preparation of clinical factor VIII concentrates; yet recovery is usually very low. Much of this loss is due to poor temperature control. A process of continuous plasma thawing was designed to overcome this. A substantial improvement resulted, with an increase in both yield and purity of factor VIII:C of > 50% in comparison to a conventional batch thaw process.This publication has 28 references indexed in Scilit:
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