Mutations affecting cysteine synthesis in Aspergillus nidulans: characterization and chromosome mapping
- 14 April 1988
- journal article
- research article
- Published by Hindawi Limited in Genetics Research
- Vol. 51 (2) , 85-88
- https://doi.org/10.1017/s0016672300024083
Abstract
Selection and mapping of mutations affecting cysteine synthesis in Aspergillus nidulans was carried out. A new locus, cysE, is described, the mutants of which are deficient in in vivo conversion of O-acetylserine to cysteine, a step mediated by cysteine synthase. Three loci (cysB, C and E) were thus found to control this step in vivo, apparently without affecting the enzyme activity in vitro. By scoring for propargylglycine sensitivity of cys mutants, chromosomal map positions were obtained for all five cysteine loci (A, B, C, D and E).This publication has 11 references indexed in Scilit:
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