Distribution of HLA-DQα and Polymarker (LDLR, GC, GYPA, HBGG, and D7S8) Alleles in Arab and Pakistani Populations Living in Abu Dhabi, United Arab Emirates
- 1 September 1997
- journal article
- other
- Published by ASTM International in Journal of Forensic Sciences
- Vol. 42 (5) , 914-918
- https://doi.org/10.1520/jfs14230j
Abstract
Randomly collected blood samples from 100 Arabs and 100 Pakistanis residing in Abu Dhabi were analyzed using the HLA-DQα and polymarker (LDLR, GC, GYPA, HBGG, D7S8) PCR based reverse dot blot systems. Allelic frequencies for each allele and observed heterozygosity for each locus were calculated. Departures from Hardy-Weinberg expectations (HWE) were determined using the unbiased estimate of the expected homozygote/heterozygote frequencies, the likelihood ratio test and the exact test. No significant departures from HWE expectations were detected.Keywords
This publication has 11 references indexed in Scilit:
- Arab Population Data on the PCR-Based Loci: HLA-DQA1, LDLR, GYPA, HBGG, D7S8, Gc, and D1S80Journal of Forensic Sciences, 1995
- Typing of DNA HLA-DQα Alleles Extracted from Human Nail Material Using Polymerase Chain ReactionJournal of Forensic Sciences, 1995
- Validation and Population Studies of the Loci LDLR, GYPA, HBGG, D7S8, and Gc (PM loci), and HLA-DQα Using a Multiplex Amplification and Typing ProcedureJournal of Forensic Sciences, 1995
- Performing the Exact Test of Hardy-Weinberg Proportion for Multiple AllelesPublished by JSTOR ,1992
- Independence of VNTR alleles defined as fixed bins.Genetics, 1992
- Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groupsGenomics, 1992
- Population Genetics of Hypervariable Loci: Analysis of PCR Based VNTR Polymorphism Within a PopulationPublished by Springer Nature ,1991
- Polymorphism of DNA sequence adjacent to human beta-globin structural gene: relationship to sickle mutation.Proceedings of the National Academy of Sciences, 1978
- SAMPLING VARIANCES OF HETEROZYGOSITY AND GENETIC DISTANCEGenetics, 1974