Phosphatidylserine: Selective Enhancer of Histamine Release
- 10 September 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 173 (4001) , 1034-1035
- https://doi.org/10.1126/science.173.4001.1034
Abstract
Phosphatidylserine, in contrast with other phospholipids, markedly enhanced histamine release from rat peritoneal mast cells induced by dextran or protein antigens. This enhancing effect was selective for dextran and protein antigens and did not extend to the action of compound 48/80 or chymotrypsin. These findings suggest a role for phosphatidylserine in the response of mast cells to antigens.Keywords
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