Preparation ofN-Arylated Heterocycles by Nucleophilic Aromatic Substitution
- 1 January 1994
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 24 (1) , 123-129
- https://doi.org/10.1080/00397919408012635
Abstract
Nucleophilic aromatic substitution of fluorobenzoates and fluorophenylnitriles with weakly basic heterocycles readily occur. This synthetic methodology is utillized to produce potent angiotensin-II antagonists.Keywords
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